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KMID : 0383819890360010047
Tuberculosis and Respiratory Diseases
1989 Volume.36 No. 1 p.47 ~ p.52
Circardian Variations of the Peripheral Blood Eosinophil Count and Pulmonary Function in the Bronchial Asthmatics
À±¼®Áß/Seok Joong Yoon
±è¿µ±Õ/±è°üÇü/Çѱ⵷/¹®È­½Ä/¼ÛÁ¤¼·/¹Ú¼ºÇÐ/Young Kyoon Kim/Kwan Hyoung Kim/Ki Don Han/Hwa Sik Moon/Jung Sup Song/Sung Hak Park
Abstract
Many investigators now believe that eosinophils are major effector cells of tissue
damage in asthma, and abnormal lung function is related to the eosinophilia. The
correlation between circardian variations of the peripheral eosinophil count and PEFR
(peak expiratory flow rate) was observed in 12 patients with bronchial asthma.
Circardian variations of the peripheral eosinophil count revealed 4 distinct types; the
first showed continuously elevated counts more than 400/§®3 (3 cases), the
second moderately decreased counts during daytime but increased during night (4 cases),
the third irregular counts (2 cases), the forth normal range less than 300/§®
3 (3 cases).
No significant relationship between the peripheral eosinophil count and PEFR was
detected for the group as a whole. But the correlation between circardian variations of
the peripheral eosinophil count and pulmonay function may be affected by a time
sequence, therefore we think the further study is needed.
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